The Royal Swedish Academy of Sciences has awarded the 2025 Nobel Prize in Chemistry to David Baker, Demis Hassabis and John Jumper for advances in computational protein design and protein structure prediction.

The prize recognizes work that has helped scientists better understand how proteins form and function, a field with major implications for medicine, biotechnology and drug discovery. Baker was honored for protein design, while Hassabis and Jumper were recognized for research that improved the prediction of protein structures.

Their contributions reflect a major step forward in the use of computing and artificial intelligence in basic science. Researchers say the methods have opened new possibilities for studying biology at the molecular level and could accelerate the development of new treatments in the years ahead.

The Nobel Prize announcement adds to a growing list of scientific breakthroughs where advanced computing is changing how researchers approach complex problems in life sciences.

Protein structure prediction

Nobel Chemistry Prize honors three scientists for protein design breakthrough